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Caenorhabditis briggsae : ウィキペディア英語版 | Caenorhabditis briggsae
''Caenorhabditis briggsae'' is a small nematode, closely related to ''Caenorhabditis elegans''. The differences between the two species are subtle. The male tail in ''C. briggsae'' has a slightly different morphology from ''C. elegans''. Other differences include changes in vulval precursor competence and the placement of the excretory duct opening. ''C. briggsae'' is frequently used to study the differences between it and the more intimately understood ''C. elegans'', especially at the DNA and protein sequence level. Several mutant strains of ''C. briggsae'' have also been isolated that facilitate genetic analysis of this organism.〔(Nematode ''C. briggsae'' Research Resource )〕 ''C. briggsae'', like ''C. elegans'', is a hermaphrodite. The genome sequence for ''C. briggsae'' was determined in 2003. == History == Ellsworth C. Dougherty first recognized the potential of ''C. briggsae'', which had been found by Margaret Briggs in a pile of leaves on the campus of Stanford University in Palo Alto, California, in 1944, and used in her MS studies under the direction of Dr. Arthur C. Giese.〔Briggs, 1946; Gochnauer, 2004〕 Briggs studied the lifecycle of what she identified as a ''Rhabditis'' species in association with bacteria and in various culture media devoid of other organisms. She showed the population could not be sustained in the absence of bacteria or even on dead bacterial cells; living bacteria were a necessary food source. However, survival of individuals was greater on some bacteria-free media than others. 〔(Ellsworth C Dougherty )〕
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